Wellcome Department of Imaging Neuroscience, London, UK
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Featured Author: Karl Friston
Karl Friston is a Wellcome Principal Research Fellow and the Scientific
Director of the Wellcome Trust Centre for Neuroimaging, University College
London, UK. He was a professor in the Institute of Neurology and holds an
honorary consultant post at the National Hospital for Neurology and
Neurosurgery, Queen Square London, UK. In 2000, he was president of the
International Organization for Human Brain Mapping.
Karl Friston was awarded the first Young Investigators Award in Human Brain
Mapping in 1996. He is a Fellow of the Academy of Medical Sciences, where he
was elected (1999) in recognition of contributions to the bio-medical
sciences. He served twice as president of the International Organization of
Human Brain Mapping. In 2003 he received the Minerva Golden Brain award.
He was elected fellow of the Royal Society in 2006.
Karl Friston is an authority on brain imaging. He invented Statistical
Parametric Mapping (SPM). SPM is used widely for analyzing functional
imaging data as well as EEG and MEG data. In 1994, his group developed
voxel-based morphometry. VBM detects differences in neuroanatomy. It is also
used clinically and as a surrogate in genetic studies. These technical
contributions were motivated by schizophrenia research and theoretical
studies of value-learning. In 1995 this work was formulated as the
disconnection hypothesis of schizophrenia. In 2003 he created dynamic causal
modelling (DCM). DCM is used to infer the architecture of distributed
systems like the brain and the principles that underlie neuronal
For more information, visit http://www.fil.ion.ucl.ac.uk/Friston/.
- Functional Imaging , Scholarpedia, 2(5):1478. (2007)
- Statistical Parametric Mapping (SPM) , Scholarpedia, 3(4):6232. (2008)
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